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Autism Autism
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Addressing a Critical Connection in Autism

We’re working to bring a first-in-class Autism treatment to market. We believe this treatment has the potential to affect both core and non-core symptoms in children with Autism. Take a closer look at what we’ve discovered, and learn more about our novel approach.

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ADHD ADHD
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ADHD from a New Approach

5.4 million children in the U.S., aged 4-17 years old (or 3-9% of school aged population) have been diagnosed with Attention-Deficit Hyperactivity Disorder (ADHD)—characterized by inattention, hyperactivity and impulsivity.

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Addiction Addiction
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Addiction: New Approaches to Reversing Behaviors

Our drug candidate, CM-1212, seeks to treat alcohol and drug addiction. Individuals addicted to drugs and alcohol lack the ability to properly digest and absorb essential nutrients. Emerging research indicates a role for amino acids in the persistence of addictive behaviors.

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Parkinson’s Disease Parkinson’s Disease
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A Treatment for Parkinson’s-Related Dyskinesia

Although no cure exists for Parkinson’s disease (PD), various medications, surgeries, and physical therapies can help improve symptoms and reduce the disease’s progression.

Our drug candidate, CM-PK, may be able to affect dopamine levels in PD patients while also improving postural instability and reducing falls.

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Schizophrenia Schizophrenia
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Schizophrenia: New Option For Treatment

The current treatment for schizophrenia, antipsychotics, can lead to numerous side effects, including drowsiness, dizziness, and rapid heartbeat.

We are developing an enzyme replacement therapy, CM-182, that may be helpful in the treatment of schizophrenia. Animal model studies of CM-182 have shown effectiveness in treating the positive symptoms of schizophrenia without sedation.

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Pipeline

Curemark has built a broad product pipeline that addresses an array of disorders.

The company’s lead asset, CM-AT, is an orally-delivered treatment for Autism Spectrum Disorder (ASD). CM-AT is designed to treat the maladaptive behaviors of irritability, agitation, hyperactivity, non-compliance and inappropriate speech in children with Autism as young as age 3. The Phase III, placebo-controlled, randomized clinical trial has been completed and the program continues to advance towards commercialization.